Mean Kinetic Temperature (MKT) in Stability Studies

 Mean Kinetic Temperature (MKT) in Stability Studies

Mean Kinetic Temperature is a useful tool used in pharmaceutical stability studies. It helps to calculate the degradation of stability sample.

As per ICH guidelines Mean Kinetic Temperature can be defined as a single calculated temperature which degrades the same amount of the drug as degraded by the different temperatures during the particular time period.

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MKT is not a simple arithmetic mean but is calculated from the temperatures of stability chambers. Many software programs are available that stores the temperature from the stability chambers and also calculate the mean kinetic temperature directly.