Difference between Sustained Release and Prolonged Release Tablets

The words sustained release and prolonged release can be used interchangeably because they mean the same thing. But the difference between sustained release tablets and prolonged release tablets is surely evident.

Sustained release tablets are in a form of dosage where a drug is administered to a patient at a given or calculated rate with the aim of maintaining a certain concentration of the administered drug over a specific period of time into the patient's system while reducing possible side effects.

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Sustain Release Tablets While prolonged release tablets are meant to effect after some time from the moment they are administered and they are known to be released in small portions over a long period of time with no specifications to time or rate of concentration.

Sustained release tablets are more of a controlled release. This happens where a capsule is made and is filled with other small pellets of drugs with different coatings that will not dissolve immediately once they are administered but will take time to release their contents at a predetermined rate.

While prolonged release tablets and capsules are aimed at delaying in administration and dissolve at a slower and constant rate into the body system with the benefit of not having to take the drugs more frequently. This is mostly for patients with chronic illness they are able to take drugs less number of times in a day.

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Prolonged release in oral dose formulations is mostly time-dependent and delayed release. Often prolonged release is targeted and intended to heal certain areas of the body system that can not be cured effectively by other ordinary drugs and ointments. 

This is different with the sustained release tablets as they are often administered slowly to maintain a particular amount of drug levels into the bloodstream during a drug administration or injection so as to maintain an efficient healing process.

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